☰ Contents · Biology (Cytology and genetics)

Organelles and the nucleus

Lessons 13–14 · 2 lessons · A. Zikiryayev, A. To‘xtayev, I. Azimov, N. Sonin. Biology. Basics of Cytology and Genetics, Grade 9, revised and expanded 5th edition. “Yangiyul Poligraph Service”, Tashkent, 2019
14

The nucleus and its structure

Textbook: pp. 44–46
GoalKnow the structure of the nucleus, chromosomes, the constancy of chromosome number and the idea of karyotype.
New words
nucleolus · yadrochachromatin · xromatinkaryotype · kariotipdiploid and haploid set · diploid va gaploid to‘plam
Explanation

The nucleus stores, copies and passes on hereditary information and controls metabolism in the cell. An interphase nucleus consists of the nuclear envelope (two membranes with pores), karyoplasm (nuclear sap), chromatin and the nucleolus. Chromatin consists of DNA and protein; during division it coils up into compact chromosomes. The centromere divides a chromosome into arms: metacentric (equal arms), submetacentric (unequal arms) and acrocentric (rod-like) chromosomes are distinguished. All somatic cells of one species have the same number of chromosomes (46 in humans, 8 in Drosophila), while sex cells have half as many; the karyotype is the number, size and shape of the chromosome set. Somatic cells are diploid (2n) and gametes haploid (n). In the nucleolus ribosomal RNA is made and ribosomes are assembled.

Worked examples
If a human somatic cell has 2n = 46 chromosomes, an egg or sperm cell has n = 46 : 2 = 23.
In Drosophila 2n = 8, so a gamete has n = 4; when two gametes fuse, the zygote again has 4 + 4 = 8 chromosomes.
Class activity

“Chromosome game”. Cut out paper homologous chromosomes (each pair the same colour and length), arrange them in pairs to make a “karyotype”, then take one from each pair to make a haploid set. Use scissors with the teacher’s help.

Practice
1
Write two main functions of the nucleus.
2
How many chromosomes does a sex cell of a cat (2n = 38) have?
3
What is a karyotype?
4
Why must sex cells have half the chromosome number of somatic cells?