☰ Contents · Biology (Cytology and genetics)

The cell cycle, mitosis and meiosis

Lessons 38–39 · 2 lessons · A. Zikiryayev, A. To‘xtayev, I. Azimov, N. Sonin. Biology. Basics of Cytology and Genetics, Grade 9, revised and expanded 5th edition. “Yangiyul Poligraph Service”, Tashkent, 2019
39

Meiosis

Textbook: pp. 99–101
GoalExplain the phases of meiosis, conjugation and crossing over and the importance of meiosis, and compare it with mitosis.
New words
meiosis · meyozconjugation · kon’yugatsiyacrossing over · krossingovergamete · gameta
Explanation

Meiosis is the division in the formation of sex cells in which a diploid (2n) cell gives 4 haploid (n) cells. It consists of two successive divisions (meiosis I and II), and DNA doubles only once before them, in interphase. In prophase I homologous chromosomes come together (conjugation) and exchange segments — crossing over; in metaphase I the pairs line up at the equator; in anaphase I whole chromosomes (not divided into chromatids) move apart to the poles, so the chromosome number halves (2n → n). Meiosis II resembles mitosis: in anaphase II the chromatids separate, giving 4 cells with n chromosomes. Thanks to meiosis the chromosome number stays constant across generations (gamete n + n = zygote 2n); independent separation of homologous pairs and crossing over increase genetic diversity, which creates combinative variation. Difference from mitosis: in mitosis there is 1 division, 2 diploid cells, genetically identical; in meiosis 2 divisions, 4 haploid cells, genetically different.

Worked examples
If 2n = 6, each gamete after meiosis has n = 3 chromosomes; the possible chromosome combinations are 2 × 2 × 2 = 8 (without crossing over).
After meiosis I a cell has n chromosomes, each with 2 chromatids (n 2c); after meiosis II, n chromosomes with 1 chromatid (n 1c).
Class activity

“Mitosis or meiosis?” Sort the cards (2 daughter cells, 4 gametes, crossing over, asexual reproduction, 2n → n, growth, conjugation) into two columns or both. Show homologous pairs “crossing over” with coloured thread.

Practice
1
How many and what kind of cells result from meiosis?
2
An animal has 2n = 20. How many chromosomes does each cell have after telophase II of meiosis?
3
What is crossing over and when does it happen?
4
Why would the chromosome number double in each generation without meiosis?