☰ Contents · Biology (Human body and health)

Erythrocytes, leukocytes and immunity

Lessons 17–18 · 2 lessons · O. Mavlonov, T. Tilavov, B. Aminov. Biology (Human body and health), Grade 8. Revised and expanded 6th edition. “O‘qituvchi” Publishing and Printing Creative House, Tashkent, 2019
18

Leukocytes (white blood cells)

Textbook: pp. 52–54
GoalExplain leukocytes, phagocytosis, kinds of immunity, vaccination and basics of HIV/AIDS.
New words
leukocyte, white blood cell · leykotsitphagocytosis · fagotsitozimmunity · immunitetvaccination · emlash
Explanation

Leukocytes are nucleated, colourless cells that can change shape; a cubic millimetre of blood has about 6–8 thousand. They are made in red marrow, lymph nodes and other organs. I.I. Mechnikov discovered phagocytosis – leukocytes swallowing and digesting microbes. Redness, swelling and pus around a splinter show leukocytes fighting. Immunity is the body’s resistance to disease agents; lymphocytes make antibodies. Immunity is innate (inherited protection present from birth) or acquired: after illness or after vaccination; a baby also receives antibodies from the mother, but this protection is temporary. In vaccination a weakened, killed or harmless part of the disease agent is introduced so the body forms immune memory without getting the disease; vaccination schedules are set by doctors and are free in Uzbekistan. Ready antibodies (serum) are given by a doctor during illness. HIV is a virus that infects immune cells; it spreads through blood and other fluids (non-sterile instruments, mother to child), not through touch, shared food or handshakes. Modern treatment can keep the virus under control and allow a long, healthy life; testing and medical supervision are important.

Worked examples
A child vaccinated against measles usually does not fall ill or has a mild illness: immune memory works.
Treating a classmate who lives with HIV with respect and help is right; sitting and playing with him or her is safe.
Class activity

“True/false” game on vaccination: write 6 statements (e.g. vaccination gives the body immune memory – true) and let a classmate answer. Reliable source: the clinic doctor.

Practice
1
What is phagocytosis and who discovered it?
2
How do innate and acquired immunity differ?
3
How does vaccination work?
4
How is HIV spread and not spread? Why should people not be shunned?