☰ Year plan · Biology

Hormones and the pituitary gland

Week 4 · Chapter 2 Hormonal Co-ordination in Living Organisms (A): hormones, how they were discovered (Starling, Jensen), plant hormones (auxins), characteristics of hormones, kinds of glands in man, the pituitary gland (master gland), its two parts and their hormones; hormonal and nervous control compared (Darslab's own table) · 3 lessons
1

What a hormone is, how hormones were found and what auxins do

Biology Sec 3 Term 1, Chapter 2: pp. 23–29
GoalDefine a hormone, say what Starling’s finding showed, and describe what auxins do in plants.
New words
hormone · a chemical made by an endocrine gland and carried by the blood to another organ, where it changes the organ’s function or growthtarget organ · the organ whose function or growth a hormone changesauxin · a plant hormone, such as indole acetic acid, made at the tip of a shoot and in budsmicrogram (µg) · one thousandth of a milligram; hormones are made in amounts of this size
Explanation

The body is coordinated by the nervous system and by hormones. Endocrine glands have no ducts: they pour their hormones straight into the blood. A hormone is a chemical made by an endocrine gland and carried by the blood to another organ, where it changes how the organ works or grows, very often by stimulating other glands or organs. Too much or too little of a hormone disturbs the body. The first hormone idea came from the work of Starling in 1905. He found that the pancreas starts to release its juice as soon as food reaches the duodenum, even when the nerves to the pancreas have been cut. So the signal could not be a nervous one. A chemical made by the lining of the duodenum must pass into the blood and stimulate the pancreas. He named such substances hormones, from a Greek word meaning activators. Plants have hormones too, but no special glands. In 1913 Boysen-Jensen showed that something made at the tip of a shoot passes down the stem and makes the part below bend towards light. Such substances are the auxins, for example indole acetic acid, made at the tip of the shoot and in buds, which then act on other parts. Auxins organize the growth and differentiation of tissues and take part in flowering and in the forming of fruit. Hormones are organic substances (proteins, amino acids or steroids), made in tiny amounts of micrograms. Their jobs include keeping the internal environment balanced, growth, sexual maturity, metabolism and development. Hormone levels also affect mood and growth, so anyone with a concern about this should ask a doctor.

What Starling observedWhat it showed
The pancreas releases juice when food reaches the duodenumsomething signals the pancreas
It still does so after its nerves are cutthe signal is not carried by nerves
The lining of the duodenum makes a chemical that passes into the blooda chemical messenger, named a hormone
Worked examples
The route of a hormone, in order.
Is it a hormone? A chemical made by a ductless gland and carried in the blood to change an organ’s growth: yes. A nerve impulse travelling along a nerve fibre: no, it is not a chemical carried in the blood. Saliva poured through a duct into the mouth: no, it does not travel in the blood.
Tiny amounts. One microgram is 1 ÷ 1000 of a milligram. A gland that makes 250 µg of a hormone in a day makes 250 ÷ 1000 = 0.25 mg. In the other direction, 0.004 mg is 0.004 × 1000 = 4 µg.
Class activity

Light and a plant tip, with a grown-up. Stand a pot of young bean seedlings beside a window so the light comes from one side only. Look each day for three days and draw the direction the tips of the stems bend. Write what the bending shows, which plant hormone the lesson links to it, and where in the plant that hormone is made. Turn the pot round on the fourth day and see what happens over the next two days.

Practice
1
Write a one-sentence definition of a hormone.
2
Why did Starling decide that the signal to the pancreas was not nervous?
3
Do plants have glands that make auxins? Where are auxins made?
4
Convert 600 µg to milligrams.