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Heredity (A): genes, alleles and Mendel’s first law

الأسبوع 10 · الوحدة الثالثة «تنوع الصفات في الكائنات الحية» (افتتاحية) والدرس الأول «الوراثة وتنوع الصفات» (١): الحمض النووي والجينات والكروموسومات والأليلات والسائد والمتنحي والطراز الجيني والمظهري وقانون مندل الأول ومربع بانيت · 3 دروس
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Dominant and recessive, genotype and phenotype

Science Prep 3 Term 1, Unit 3: pp. 64–70
GoalUse the words dominant and recessive, homozygous and heterozygous, genotype and phenotype with letters.
New words
dominant allele · the allele whose trait shows when the two alleles differgenotype · the pair of alleles an organism has, for example Ppphenotype · the trait that can be seen, for example purple flowers
Explanation

When the two alleles of a gene differ, the one that shows is dominant and the one that is hidden is recessive. We write the dominant allele with a capital letter and the recessive one with the small form of the same letter, taking the first letter of the dominant trait: for purple flowers, P and p. Complete dominance means that the dominant trait fully hides the recessive one. Homozygous means two identical alleles (PP or pp). Heterozygous means two different alleles (Pp). The genotype is the pair of alleles, and the phenotype is the trait we see. So PP and Pp have the same phenotype, purple, but different genotypes, while pp is white. The recessive trait appears only with pp. Careful: dominant does not mean stronger, better or more common. We use pea plants and invented organisms for our crosses, because human traits such as eye or hair colour depend on several genes and our one-gene models are only simple models.

GenotypeAllelesPhenotype
PPhomozygous dominantpurple
Ppheterozygouspurple
pphomozygous recessivewhite
Worked examples
TraitDominantRecessive
stemtallshort
flower colourpurplewhite
seed shaperoundwrinkled
seed colouryellowgreen
Mendel’s seven pea traits, dominant first: tall or short stem, axial or terminal flowers, purple or white flowers, inflated or constricted pods, green or yellow pods, round or wrinkled seeds, yellow or green seeds. For the seed colour, Y is yellow (dominant) and y is green (recessive).
A plant with the genotype Yy has yellow seeds. Its genotype has one dominant and one recessive allele, so it is heterozygous, and the phenotype is yellow because Y hides y. A plant with yy has green seeds.
Two plants both look purple. Do they have the same genotype? Not necessarily: one may be PP and the other Pp. We cannot tell the genotype from the phenotype alone.
Class activity

Genotype cards. Make cards with the genotypes TT, Tt and tt for tall (T) and short (t) pea plants. Under each card write the phenotype and tick homozygous or heterozygous. Shuffle and sort. Then find the mistake in: “a dominant allele is the one that is more common”. Draw the seven pea traits as small symbols.

Practice
1
In peas, T is for tall (dominant) and t is for short. What is the phenotype of Tt?
2
Which genotype gives a short plant?
3
Classify RR, Rr and rr as homozygous or heterozygous.
4
A student says dominant means “stronger”. Correct this.
5
Why do we say we cannot always find the genotype from the phenotype?